Mergers and acquisitions (M&A) have become one of the most important strategic approaches adopted by organizations to achieve business expansion, improve operational efficiency, gain competitive advantage, and enhance long-term organizational performance. Although financial resources, technology, and strategic planning play significant roles in determining the success of mergers and acquisitions, organizational culture has emerged as a critical factor influencing post-merger integration and overall business success. Differences in organizational values, beliefs, leadership styles, communication patterns, and employee behavior often create cultural conflicts that hinder integration, reduce employee commitment, and negatively affect organizational performance. Therefore, understanding the role of organizational culture is essential for ensuring the successful implementation of mergers and acquisitions.The present study examines the role of organizational culture in enhancing the success of mergers and acquisitions by analysing how cultural compatibility, employee engagement, leadership support, communication effectiveness, and shared organizational values contribute to successful post-merger integration.